No evidence that established type 2 diabetes susceptibility variants in the PPARG and KCNJ11 genes have pleiotropic effects on early growth.

AIMS/HYPOTHESIS: The P12A variant in the PPARG gene and the E23K polymorphism in KCNJ11 are both known to influence individual predisposition to type 2 diabetes. If the effect of these variants on insulin secretion and action were to extend to an influence on early growth (which is largely mediated...

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Bibliographic Details
Main Authors: Bennett, A, Sovio, U, Ruokonen, A, Martikainen, H, Pouta, A, Hartikainen, A, Franks, S, Elliott, P, Järvelin, MR, McCarthy, M
Format: Journal article
Language:English
Published: 2008