No evidence that established type 2 diabetes susceptibility variants in the PPARG and KCNJ11 genes have pleiotropic effects on early growth.
AIMS/HYPOTHESIS: The P12A variant in the PPARG gene and the E23K polymorphism in KCNJ11 are both known to influence individual predisposition to type 2 diabetes. If the effect of these variants on insulin secretion and action were to extend to an influence on early growth (which is largely mediated...
Main Authors: | , , , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2008
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