NAADP Activates two-pore channels on t cell cytolytic granules to stimulate exocytosis and killing
A cytotoxic T lymphocyte (CTL) kills an infected or tumorigenic cell by Ca2+-dependent exocytosis of cytolytic granules at the immunological synapse formed between the two cells. Although inositol 1,4,5-trisphosphate (IP3)-mediated Ca2+ release from the endoplasmic reticulum activates the store-oper...
मुख्य लेखकों: | , , , , , , , , , , , |
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स्वरूप: | Journal article |
भाषा: | English |
प्रकाशित: |
2012
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