MC1R is a potent regulator of PTEN after UV exposure in melanocytes.

The individuals carrying melanocortin-1 receptor (MC1R) variants, especially those associated with red hair color, fair skin, and poor tanning ability (RHC trait), are more prone to melanoma; however, the underlying mechanism is poorly defined. Here, we report that UVB exposure triggers phosphatase...

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Bibliographic Details
Main Authors: Cao, J, Wan, L, Hacker, E, Dai, X, Lenna, S, Jimenez-Cervantes, C, Wang, Y, Leslie, N, Xu, G, Widlund, H, Ryu, B, Alani, R, Dutton-Regester, K, Goding, C, Hayward, N, Wei, W, Cui, R
Format: Journal article
Language:English
Published: 2013