A selective sweep driven by pyrimethamine treatment in southeast asian malaria parasites.

Malaria parasites (Plasmodium falciparum) provide an excellent system in which to study the genomic effects of strong selection in a recombining eukaryote because the rapid spread of resistance to multiple drugs during the last the past 50 years has been well documented, the full genome sequence and...

Полное описание

Библиографические подробности
Главные авторы: Nair, S, Williams, J, Brockman, A, Paiphun, L, Mayxay, M, Newton, P, Guthmann, J, Smithuis, F, Hien, T, White, N, Nosten, F, Anderson, T
Формат: Journal article
Язык:English
Опубликовано: 2003