Crohn's disease and the NOD2 gene: a role for paneth cells.

BACKGROUND and AIMS: The NOD2 gene, which is strongly associated with susceptibility to Crohn's disease (CD) of the terminal ileum, interacts with bacterial lipopolysaccharide (LPS), inducing cellular activation. However, the mechanisms by which NOD2 mutations cause terminal ileitis are unknow...

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Những tác giả chính: Lala, S, Ogura, Y, Osborne, C, Hor, S, Bromfield, A, Davies, S, Ogunbiyi, O, Nuñez, G, Keshav, S
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 2003