Metallo supramolecular cylinders inhibit HIV-1 TAR-TAT complex formation and viral replication in cellulo

Shape-selective recognition of nucleic acid structures by supramolecular drugs offers the potential to treat disease. The Trans Activation Response (TAR) region is a region of high secondary structure within the human immunodeficiency virus-1 (HIV-1) RNA that complexes with the virus-encoded Transac...

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Bibliographic Details
Main Authors: Cardo, L, Nawroth, I, Cail, P, McKeating, J, Hannon, M
Format: Journal article
Published: Springer Nature 2018