Blood-stage challenge for malaria vaccine efficacy trials: a pilot study with discussion of safety and potential value.

There is increasing interest in malaria vaccines targeting the asexual blood stage of Plasmodium falciparum. Without accepted immunologic correlates of clinical protection, challenge studies are useful for assessing the efficacy of candidate vaccines in vivo in healthy volunteers. We report a pilot...

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Bibliographic Details
Main Authors: Sanderson, F, Andrews, L, Douglas, A, Hunt-Cooke, A, Bejon, P, Hill, A
Format: Journal article
Language:English
Published: 2008