The functional "KL-VS" variant of KLOTHO is not associated with type 2 diabetes in 5028 UK Caucasians

<p style="text-align:justify;"> <b>Background:</b> Klotho has an important role in insulin signalling and the development of ageing-like phenotypes in mice. The common functional "KL-VS" variant in the KLOTHO (KL) gene is associated with longevity in humans but...

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Bibliographic Details
Main Authors: Freathy, R, Weedon, M, Melzer, D, Shields, B, Hitman, G, Walker, M, McCarthy, M, Hattersley, A, Frayling, T
Format: Journal article
Language:English
Published: BioMed Central 2006