ATP modulation of ATP-sensitive potassium channel ATP sensitivity varies with the type of SUR subunit.

ATP-sensitive potassium (K(ATP)) channels comprise Kir and SUR subunits. Using recombinant K(ATP) channels expressed in Xenopus oocytes, we observed that MgATP (100 microm) block of Kir6.2/SUR2A currents gradually declined with time, whereas inhibition of Kir6.2/SUR1 or Kir6.2DeltaC36 currents did n...

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Príomhchruthaitheoirí: Song, D, Ashcroft, F
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: 2001