Understanding the mechanism of Adenovirus endosomal escape

<p>Adenoviruses (AdV) are non-enveloped dsDNA viruses that cause respiratory and gastrointestinal diseases and are commonly used as vaccine and gene therapy vectors. In order to replicate inside a host cell, AdV must first penetrate the endosomal membrane and gain access to the cytosol. A high...

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Bibliographic Details
Main Author: Sawtell, K
Other Authors: Grünewald, K
Format: Thesis
Language:English
Published: 2020
Subjects: