Common variation in the LMNA gene (encoding lamin A/C) and type 2 diabetes: association analyses in 9,518 subjects.

Mutations in the LMNA gene (encoding lamin A/C) underlie familial partial lipodystrophy, a syndrome of monogenic insulin resistance and diabetes. LMNA maps to the well-replicated diabetes-linkage region on chromosome 1q, and there are reported associations between LMNA single nucleotide polymorphism...

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Bibliographic Details
Main Authors: Owen, K, Groves, C, Hanson, R, Knowler, W, Shuldiner, A, Elbein, S, Mitchell, B, Froguel, P, Ng, M, Chan, J, Jia, W, Deloukas, P, Hitman, G, Walker, M, Frayling, T, Hattersley, A, Zeggini, E, McCarthy, M
Format: Journal article
Language:English
Published: 2007