Uncertainty and variability in models of the cardiac action potential: Can we build trustworthy models?

<p>Cardiac electrophysiology models have been developed for over 50 years, and now include detailed descriptions of individual ion currents and sub-cellular calcium handling. It is commonly accepted that there are many uncertainties in these systems, with quantities such as ion channel kinetic...

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Bibliographic Details
Main Authors: Johnstone, R, Chang, E, Bardenet, R, de Boer, T, Gavaghan, D, Pathmanathan, P, Clayton, R, Mirams, G
Format: Journal article
Published: Elsevier 2015