A protein pore with a single polymer chain tethered within the lumen

A transmembrane protein pore with a single 5000 Da poly(ethylene glycol) (PEG) molecule attached covalently within the channel lumen has been constructed from seven staphylococcal α-hemolysin subunits. The modified heptamer is stable and can be purified by electrophoresis in sodium dodecyl sulfate,...

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Bibliographic Details
Main Authors: Howorka, S, Movileanu, L, Lu, X, Magnon, M, Cheley, S, Braha, O, Bayley, H
Format: Journal article
Language:English
Published: 2000