Structure and mechanism of a canonical poly(ADP-ribose) glycohydrolase.

Poly(ADP-ribosyl)ation is a reversible post-translational protein modification involved in the regulation of a number of cellular processes including DNA repair, chromatin structure, mitosis, transcription, checkpoint activation, apoptosis and asexual development. The reversion of poly(ADP-ribosyl)a...

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Bibliographic Details
Main Authors: Dunstan, MS, Barkauskaite, E, Lafite, P, Knezevic, C, Brassington, A, Ahel, M, Hergenrother, P, Leys, D, Ahel, I
Format: Journal article
Language:English
Published: 2012