The asymmetric synthesis of (2R,3R)- and (2R,3S)-3-methyl-aspartates via an enantiodiscrimination strategy
The enolate of (S)-N,N′-bis-(p-methoxybenzyl)-3-isopropylpiperazine-2,5-dione exhibits high levels of enantiodiscrimination towards racemic 2-bromo-propionate esters to afford adducts containing two new stereogenic centres which may be deprotected to afford (2R,3R)-3-methyl-aspartates or epimerised...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2001
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