A novel strategy for inducing enhanced mucosal HIV-1 antibody responses in an anti-inflammatory environment
Prophylactic vaccination against HIV-1 sexual transmission will probably require antibody elicitation at genital mucosal surfaces. However, HIV-1 envelope glycoprotein (Env)-based antigens are weakly immunogenic, particularly when applied mucosally. The polyanion PRO 2000 is safe for human vaginal a...
Päätekijät: | , , , , , , , |
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Aineistotyyppi: | Journal article |
Kieli: | English |
Julkaistu: |
Public Library of Science
2011
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Aiheet: |