A novel strategy for inducing enhanced mucosal HIV-1 antibody responses in an anti-inflammatory environment

Prophylactic vaccination against HIV-1 sexual transmission will probably require antibody elicitation at genital mucosal surfaces. However, HIV-1 envelope glycoprotein (Env)-based antigens are weakly immunogenic, particularly when applied mucosally. The polyanion PRO 2000 is safe for human vaginal a...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Wegmann, F, Krashias, G, Lühn, K, Laamanen, K, Vieira, S, Jeffs, S, Shattock, R, Sattentau, Q
Формат: Journal article
Хэл сонгох:English
Хэвлэсэн: Public Library of Science 2011
Нөхцлүүд: