Inferring structural properties of protein-DNA binding using high-throughput sequencing. The paradigm of GATA1, KLF1 and their complexes GATA1/FOG1 and GATA1/KLF1. Insights into the transcriptional regulation of the erythroid cell lineage.

<p>GATA1 and KLF1 are transcription factors that regulate genes which are important for the development of erythroid cells. The GATA1 transcriptional co-factor FOG1 has been shown to be essential in a wide range of GATA1 dependent cellular functions. Here we tried to understand the diverse mec...

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Bibliographic Details
Main Author: Oikonomopoulos, S
Other Authors: Ragoussis, J
Format: Thesis
Language:English
Published: 2014
Subjects: