Allosteric initiation and regulation of catalysis with a molecular knot

Molecular knots occur in DNA, proteins, and other macromolecules. However, the benefits that can potentially arise from tying molecules in knots are, for the most part, unclear. Here, we report on a synthetic molecular pentafoil knot that allosterically initiates or regulates catalyzed chemical reac...

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Bibliographic Details
Main Authors: Marcos, V, Stephens, A, Jaramillo-Garcia, J, Nussbaumer, A, Woltering, S, Valero, A, Lemonnier, J, Vitorica-Yrezabal, I, Leigh, D
Format: Journal article
Published: American Association for the Advancement of Science 2016