Role of the influenza virus heterotrimeric RNA polymerase complex in the initiation of replication.

Both transcription and replication of the influenza virus RNA genome are catalysed by a virus-specific RNA polymerase. Recently, an in vitro assay, based on the synthesis of pppApG, for the initiation of replication by recombinant RNA polymerase in the absence of added primer was described. Here, th...

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Bibliographic Details
Main Authors: Deng, T, Sharps, J, Brownlee, G
Format: Journal article
Language:English
Published: 2006