Cytotoxic T lymphocytes form an antigen-independent ring junction.

Immunological synapses are organized cell-cell junctions between T lymphocytes and APCs composed of an adhesion ring, the peripheral supramolecular activation cluster (pSMAC), and a central T cell receptor cluster, the central supramolecular activation cluster (cSMAC). In CD8(+) cytotoxic T lymphocy...

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Bibliographic Details
Main Authors: Somersalo, K, Anikeeva, N, Sims, T, Thomas, V, Strong, R, Spies, T, Lebedeva, T, Sykulev, Y, Dustin, M
Format: Journal article
Language:English
Published: 2004