CCL11 blocks IL-4 and GM-CSF signaling in hematopoietic cells and hinders dendritic cell differentiation via suppressor of cytokine signaling expression.

CCL11 blocks IL-4 and GM-CSF signaling in hematopoietic cells and hinders dendritic cell differentiation via suppressor of cytokine signaling expression.

The chemokine eotaxin/CCL11 is an important mediator of leukocyte migration, but its effect on inflammatory cytokine signaling has not been explored. In this study, we find that CCL11 induces suppressor of cytokine signaling (SOCS)1 and SOCS3 expression in murine macrophages, human monocytes, and de...

書誌詳細
主要な著者:	Stevenson, N, Addley, MR, Ryan, E, Boyd, C, Carroll, H, Paunovic, V, Bursill, C, Miller, H, Channon, K, McClurg, A, Armstrong, M, Coulter, W, Greaves, D, Johnston, J
フォーマット:	Journal article
言語:	English
出版事項:	2009

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