Simultaneous and enantiospecific quantification of primaquine and carboxyprimaquine in human plasma using liquid chromatography-tandem mass spectrometry

Background The enantiomers of the 8-aminoquinoline anti-malarial primaquine have different pharmacological properties. Development of an analytical method for simultaneous quantification of the enantiomers of primaquine and its metabolite, carboxyprimaquine, will support clinical pharmacometric asse...

全面介紹

書目詳細資料
Main Authors: Hanpithakpong, W, Day, NPJ, White, NJ, Tarning, J
格式: Journal article
語言:English
出版: BioMed Central 2022