Simultaneous and enantiospecific quantification of primaquine and carboxyprimaquine in human plasma using liquid chromatography-tandem mass spectrometry

Simultaneous and enantiospecific quantification of primaquine and carboxyprimaquine in human plasma using liquid chromatography-tandem mass spectrometry

Background The enantiomers of the 8-aminoquinoline anti-malarial primaquine have different pharmacological properties. Development of an analytical method for simultaneous quantification of the enantiomers of primaquine and its metabolite, carboxyprimaquine, will support clinical pharmacometric asse...

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Dettagli Bibliografici
Autori principali:	Hanpithakpong, W, Day, NPJ, White, NJ, Tarning, J
Natura:	Journal article
Lingua:	English
Pubblicazione:	BioMed Central 2022

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