Design, synthesis and evaluation of molecularly targeted hypoxia-activated prodrugs
Regions of insufficient oxygen supply-hypoxia-occur in diverse contexts across biology in both healthy and diseased organisms. The difference in the chemical environment between a hypoxic biological system and one with normal oxygen levels provides an opportunity for targeting compound delivery to h...
Main Authors: | , , , , , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
Nature Publishing Group
2016
|