Enhancing the identification of phosphopeptides from putative basophilic kinase substrates using Ti (IV) based IMAC enrichment.

Metal and metal oxide chelating-based phosphopeptide enrichment technologies provide powerful tools for the in-depth profiling of phosphoproteomes. One weakness inherent to current enrichment strategies is poor binding of phosphopeptides containing multiple basic residues. The problem is exacerbated...

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Bibliographic Details
Main Authors: Zhou, H, Low, T, Hennrich, M, van der Toorn, H, Schwend, T, Zou, H, Mohammed, S, Heck, A
Format: Journal article
Language:English
Published: 2011