Generation of novel human MHC class II mutant B-cell lines by integrating YAC DNA into a cell line homozygously deleted for the MHC class II region.

The human B lymphoblastoid cell line (LCL) 721.174 sustains a large homozygous deletion in the major histocompatibility complex (MHC) class II region that results in an absence of DQ and DR molecules as well as a deficiency in the assembly and transport of class I molecules to the cell surface. The...

תיאור מלא

מידע ביבליוגרפי
Main Authors: Fabb, SA, Davies, A, Correa, I, Kelly, A, Mackie, C, Trowsdale, J, Ragoussis, I
פורמט: Journal article
שפה:English
יצא לאור: 1997