In vitro base excision repair using mammalian cell extracts.

Base excision repair (BER) is an essential cellular mechanism that maintains genome stability by repairing DNA damage, such as DNA base lesions, base loss (AP sites) and single strand breaks, generated through endogenous metabolism or via exogenous mutagens. Therefore, in vitro BER assays are import...

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Bibliographic Details
Main Authors: Parsons, J, Dianov, G
Format: Journal article
Language:English
Published: 2012