Progress and prospects: the design and production of plasmid vectors.
Plasmid DNA (pDNA) expression vectors are fundamental to all forms of non-viral gene transfer. In this review, we discuss principles of pDNA design and production including the impact of bacterially derived sequences on transgene expression and minicircle approaches to minimize their effects. The im...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2009
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