Inhibition of mycobacterial arylamine N-acetyltransferase contributes to anti-mycobacterial activity of Warburgia salutaris.

Inhibition of mycobacterial arylamine N-acetyltransferase contributes to anti-mycobacterial activity of Warburgia salutaris.

अन्य संस्करण दिखाएं (1)

In this study, we show that extracts and a purified compound of Warburgia salutaris exhibit anti-mycobacterial activity against Mycobacterium tuberculosis H37Rv and Mycobacterium bovis BCG Pasteur. The extracts did not inhibit growth of Escherichia coli and were not toxic to cultured mammalian macro...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों:	Madikane, V, Bhakta, S, Russell, A, Campbell, W, Claridge, T, Elisha, BG, Davies, S, Smith, P, Sim, E
स्वरूप:	Journal article
भाषा:	English
प्रकाशित:	2007

समान संसाधन

Inhibition of mycobacterial arylamine N-acetyltransferase contributes to anti-mycobacterial activity of Warburgia salutaris
द्वारा: Madikane, V, और अन्य
प्रकाशित: (2007)

Structural Studies on the Mycobacterial Arylamine N-Acetyltransferases
द्वारा: Abuhammad, A, और अन्य
प्रकाशित: (2010)

Piperidinols that show anti-tubercular activity as inhibitors of arylamine N-acetyltransferase: an essential enzyme for mycobacterial survival inside macrophages
द्वारा: Abuhammad, A, और अन्य
प्रकाशित: (2012)

Piperidinols that show anti-tubercular activity as inhibitors of arylamine N-acetyltransferase: an essential enzyme for mycobacterial survival inside macrophages.
द्वारा: Areej Abuhammad, और अन्य
प्रकाशित: (2012-01-01)

Warburgia Salutaris Metabolites of Medicinal Value – A Review
द्वारा: Vuyiseka Nkqenkqa, और अन्य
प्रकाशित: (2023-11-01)

Structure and mechanism of arylamine N-acetyltransferases.
द्वारा: Westwood, I, और अन्य
प्रकाशित: (2006)

Identification of arylamine N-acetyltransferase inhibitors as an approach towards novel anti-tuberculars.
द्वारा: Westwood, I, और अन्य
प्रकाशित: (2010)

Arylamine N-acetyltransferase in adult mouse brain
द्वारा: Mo, M, और अन्य
प्रकाशित: (2004)

An approach to identifying novel substrates of bacterial arylamine N-acetyltransferases.
द्वारा: Brooke, E, और अन्य
प्रकाशित: (2003)

Selective small molecule inhibitors of the potential breast cancer marker, human arylamine N-acetyltransferase 1, and its murine homologue, mouse arylamine N-acetyltransferase 2.
द्वारा: Russell, A, और अन्य
प्रकाशित: (2009)

Differences between murine arylamine N-acetyltransferase type 1 and human arylamine N-acetyltransferase type 2 defined by substrate specificity and inhibitor binding
द्वारा: Laurieri, N, और अन्य
प्रकाशित: (2014)

Characterization of the putative operon containing arylamine N-acetyltransferase (nat) in Mycobacterium bovis BCG.
द्वारा: Anderton, M, और अन्य
प्रकाशित: (2006)

Neuroendocrine expression of mouse arylamine N-acetyltransferase 2
द्वारा: Wakefield, L, और अन्य
प्रकाशित: (2006)

Mapping the genes for arylamine N-acetyltransferases
द्वारा: Fakis, G
प्रकाशित: (2000)

Arylamine N-acetyltransferases: structural and functional implications of polymorphisms.
द्वारा: Sim, E, और अन्य
प्रकाशित: (2008)

Novel small-molecule inhibitors of arylamine N-acetyltransferases: drug discovery by high-throughput screening.
द्वारा: Westwood, I, और अन्य
प्रकाशित: (2011)

Isolation, characterization, and biological evaluation of a potent anti-malarial drimane sesquiterpene from Warburgia salutaris stem bark
द्वारा: Zoxolo N. Nyaba, और अन्य
प्रकाशित: (2018-08-01)

Arylamine N-acetyltransferase expression during murine heart development
द्वारा: Wakefield, L, और अन्य
प्रकाशित: (2004)

Structural investigation of mutant Mycobacterium smegmatis arylamine N-acetyltransferase: a model for a naturally occurring functional polymorphism in Mycobacterium tuberculosis arylamine N-acetyltransferase.
द्वारा: Kawamura, A, और अन्य
प्रकाशित: (2003)

Expression of the genes for arylamine N-acetyltransferases in mice
द्वारा: Boukouvala, S, और अन्य
प्रकाशित: (2002)

Comparison of the Arylamine N-acetyltransferase from Mycobacterium marinum and Mycobacterium tuberculosis.
द्वारा: Fullam, E, और अन्य
प्रकाशित: (2009)

Probing the architecture of the Mycobacterium marinum arylamine N-acetyltransferase active site.
द्वारा: Abuhammad, A, और अन्य
प्रकाशित: (2010)

Iso-Mukaadial Acetate from <i>Warburgia salutaris</i> Enhances Glucose Uptake in the L6 Rat Myoblast Cell Line
द्वारा: Nontokozo Z. Msomi, और अन्य
प्रकाशित: (2019-09-01)

Design, synthesis and structure-activity relationships of 3,5-diaryl-1H-pyrazoles as inhibitors of arylamine N-acetyltransferase.
द्वारा: Fullam, E, और अन्य
प्रकाशित: (2013)

Design, synthesis and structure-activity relationships of 3,5-diaryl-1H-pyrazoles as inhibitors of arylamine N-acetyltransferase.
द्वारा: Fullam, E, और अन्य
प्रकाशित: (2013)

Synthesis and in vitro evaluation of novel small molecule inhibitors of bacterial arylamine N-acetyltransferases (NATs).
द्वारा: Brooke, E, और अन्य
प्रकाशित: (2003)

Over-expression, purification, and characterization of recombinant human arylamine N-acetyltransferase 1.
द्वारा: Wang, H, और अन्य
प्रकाशित: (2005)

Mycobacterial Aminoglycoside Acetyltransferases: A Little of Drug Resistance, and a Lot of Other Roles
द्वारा: Fernando Sanz-García, और अन्य
प्रकाशित: (2019-01-01)

Eukaryotic arylamine N-acetyltransferase. Investigation of substrate specificity by high-throughput screening.
द्वारा: Kawamura, A, और अन्य
प्रकाशित: (2005)

Arylamine N-acetyltransferase 2 gene polymorphism in an Algerian population
द्वारा: Hiba Chelouti, और अन्य
प्रकाशित: (2017-08-01)

Biochemical Characterization of Arylamine N-acetyltransferases From Vibrio vulnificus
द्वारा: Xinning Liu, और अन्य
प्रकाशित: (2021-01-01)

Small molecule colorimetric probes for specific detection of human arylamine N-acetyltransferase 1, a potential breast cancer biomarker.
द्वारा: Laurieri, N, और अन्य
प्रकाशित: (2010)

Profiling mycobacterial communities in pulmonary nontuberculous mycobacterial disease.
द्वारा: Steven A Cowman, और अन्य
प्रकाशित: (2018-01-01)

Protein-ligand interactions of arylamine N-acetyltransferase from Mycobacterium smegmatis
द्वारा: Brooke, E
प्रकाशित: (2003)

Polymorphisms of arylamine N-acetyltransferase2 and risk of lung and colorectal cancer
द्वारा: Amjad Mahasneh, और अन्य
प्रकाशित: (2012-01-01)

Arylamine N-Acetyltransferase 1 Activity is Regulated by the Protein Acetylation Status
द्वारा: Raúl A. Salazar-González, और अन्य
प्रकाशित: (2022-01-01)

Hamster arylamine N-acetyltransferase 2: Investigation of substrate specificity by high-through-put screening
द्वारा: Kawamura, A, और अन्य
प्रकाशित: (2004)

Sensing of mycobacterial arabinogalactan by galectin-9 exacerbates mycobacterial infection
द्वारा: Wu, X, और अन्य
प्रकाशित: (2021)

Molecular assessment of mycobacterial burden in the treatment of nontuberculous mycobacterial disease
द्वारा: Huw C. Ellis, और अन्य
प्रकाशित: (2023-03-01)

Distribution of arylamine N-acetyltransferase 2 (NAT2) genotypes among Omanis
द्वारा: Musbah O. M. Tanira, और अन्य
प्रकाशित: (2003-04-01)