Combined point-of-care nucleic acid and antibody testing for SARS-CoV-2 following emergence of D614G spike variant

Rapid COVID-19 diagnosis in the hospital is essential, although this is complicated by 30%–50% of nose/throat swabs being negative by SARS-CoV-2 nucleic acid amplification testing (NAAT). Furthermore, the D614G spike mutant dominates the pandemic and it is unclear how serological tests designed to d...

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Main Authors: Mlcochova, P, Collier, D, Ritchie, A, Assennato, SM, Hosmillo, M, Goel, N, Meng, B, Chatterjee, K, Mendoza, V, Temperton, N, Kiss, L, James, LC, Ciazynska, KA, Xiong, X, Briggs, JAG, Nathan, JA, Mescia, F, Bergamaschi, L, Zhang, H, Barmpounakis, P, Demeris, N, Skells, R, Lyons, PA, Bradley, J, Baker, S, Allain, JP, Smith, KGC, Bousfield, R, Wilson, M, Sparkes, D, Amoroso, G, Gkrania-Klotsas, E, Hardwick, S, Boyle, A, Goodfellow, I, Gupta, RK, Dougan, G, Gupta, R, Lehner, PJ, Lyons, P, Matheson, NJ, Toshner, M, Weekes, MP, Brown, N, Curran, M, Palmar, S, Enoch, D, Chapman, D, Shaw, A
Format: Journal article
Language:English
Published: Cell Press 2020