Understanding the genetic relationship between key effectors of DNA interstrand crosslink repair

<p>With each cell division, our whole genome is duplicated in an error-free and controlled manner. Failure to do so leads to genomic instability. DNA interstrand crosslinks (ICLs) are particularly toxic DNA lesions as when left unrepaired, they are able to block replication producing devastati...

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Bibliografische gegevens
Hoofdauteur: Brolih, S
Andere auteurs: McHugh, P
Formaat: Thesis
Gepubliceerd in: 2016