An automated high-throughput system for phenotypic screening of chemical libraries on C. elegans and parasitic nematodes.

Parasitic nematodes infect hundreds of millions of people and farmed livestock. Further, plant parasitic nematodes result in major crop damage. The pipeline of therapeutic compounds is limited and parasite resistance to the existing anthelmintic compounds is a global threat. We have developed an INV...

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Bibliographic Details
Main Authors: Partridge, F, Brown, A, Buckingham, S, Willis, N, Wynne, G, Forman, R, Else, K, Morrison, A, Matthews, J, Russell, A, Lomas, D, Sattelle, D
Format: Journal article
Language:English
Published: Elsevier 2017