Genetic factors of the disease course after sepsis: a genome-wide study for 28 day mortality

Sepsis is the dysregulated host response to an infection which leads to life-threatening organ dysfunction that varies by host genomic factors. We conducted a genome-wide association study (GWAS) in 740 adult septic patients and focused on 28day mortality as outcome. Variants with suggestive evidenc...

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Bibliographic Details
Main Authors: Scherag, A, Schöneweck, F, Kesselmeier, M, Taudien, S, Platzer, M, Felder, M, Sponholz, C, Rautanen, A, Hill, A, Hinds, C, Hossain, H, Suttorp, N, Kurzai, O, Slevogt, H, Giamarellos-Bourboulis, E, Armaganidis, A, Trips, E, Scholz, M, Brunkhorst, F
Format: Journal article
Language:English
Published: Elsevier 2016