Access to a guanacastepene and cortistatin-related skeleton via ethynyl lactone Ireland−Claisen rearrangement and transannular (4 + 3)-cycloaddition of an azatrimethylenemethane diyl
Heating a 2,5-furanocyclic (2-azidoethyl)allene initiates a cascade reaction comprising azide–allene cycloaddition, loss of nitrogen, and azatrimethylenemethane (ATMM) diyl–furan transannular (4+3)-cycloaddition. The major product of this reaction contains the pentacyclic core common to guanacastepe...
| Glavni autori: | , , , |
|---|---|
| Format: | Journal article |
| Izdano: |
American Chemical Society
2017
|