Transcriptional interference and termination between duplicated alpha-globin gene constructs suggests a novel mechanism for gene regulation.

Transcriptional interference and termination between duplicated alpha-globin gene constructs suggests a novel mechanism for gene regulation.

The interesting possibility that transcriptional interference can occur between eukaryotic genes was raised by studies on the avian leukosis retrovirus (ALV) which showed that deletion of the promoter in the 5' long terminal repeat (LTR) activates the 3' LTR promoter, linked to a downstrea...

Descripció completa

Dades bibliogràfiques
Autor principal:	Proudfoot, N
Format:	Journal article
Idioma:	English
Publicat:	1986

Ítems similars

The structure of a human alpha-globin pseudogene and its relationship to alpha-globin gene duplication.
per: Proudfoot, N, et al.
Publicat: (1980)

Transcriptional promiscuity of the human alpha-globin gene.
per: Whitelaw, E, et al.
Publicat: (1989)

Transcriptional activity of the human pseudogene psi alpha globin compared with alpha globin, its functional gene counterpart.
per: Whitelaw, E, et al.
Publicat: (1983)

Studies on messenger RNA 3' end formation in globin genes: a transcriptional interference model for globin gene switching.
per: Proudfoot, N, et al.
Publicat: (1985)

Transcriptional regulation of human zeta and psi zeta globin genes.
per: Norman, C, et al.
Publicat: (1987)

Transcriptional analysis of human zeta globin genes.
per: Proudfoot, N, et al.
Publicat: (1984)

The primary transcription unit of the human alpha 2 globin gene defined by quantitative RT/PCR.
per: Owczarek, C, et al.
Publicat: (1992)

The transcriptional regulation of the zeta-globin gene
per: Liu, S
Publicat: (2022)

Structure and in vitro transcription of human globin genes.
per: Proudfoot, N, et al.
Publicat: (1980)

Intergenic transcription in the human beta-globin gene cluster.
per: Plant, K, et al.
Publicat: (2001)

Transcriptional and translational analysis of the human theta globin gene.
per: Leung, S, et al.
Publicat: (1989)

Nucleotide sequence of the 3' terminal third of rabbit alpha-globin messenger RNA: comparison with human alpha-globin messenger RNA.
per: Proudfoot, N, et al.
Publicat: (1977)

The 3' terminal sequences of human alpha and beta globin messenger RNAs: comparison with rabbit globin messenger RNA.
per: Proudfoot, N, et al.
Publicat: (1976)

Strong polyadenylation and weak pausing combine to cause efficient termination of transcription in the human Ggamma-globin gene.
per: Plant, K, et al.
Publicat: (2005)

Long-range regulation of alpha-globin gene expression.
per: Higgs, D, et al.
Publicat: (2008)

Independent recombination events between the duplicated human alpha globin genes; implications for their concerted evolution.
per: Higgs, D, et al.
Publicat: (1984)

Globin gene transcripts can utilize histone gene 3' end processing signals.
per: Whitelaw, E, et al.
Publicat: (1986)

GEOGRAPHIC-DISTRIBUTION OF ALPHA-GLOBIN AND BETA-GLOBIN GENE-CLUSTER POLYMORPHISMS
per: Wainscoat, J, et al.
Publicat: (1989)

Negative regulation of the human embryonic globin genes zeta and epsilon.
per: Lamb, P, et al.
Publicat: (1989)

Dicer-dependent turnover of intergenic transcripts from the human beta-globin gene cluster.
per: Haussecker, D, et al.
Publicat: (2005)

Understanding alpha-globin gene regulation: Aiming to improve the management of thalassemia.
per: Higgs, D, et al.
Publicat: (2005)

Long-range regulation of alpha globin gene expression during erythropoiesis.
per: Higgs, D, et al.
Publicat: (2008)

Tissue-specific histone modification and transcription factor binding in alpha globin gene expression.
per: De Gobbi, M, et al.
Publicat: (2007)

Distinct negative regulation of the human embryonic globin genes zeta and epsilon.
per: Watt, P, et al.
Publicat: (1993)

Molecular cloning of human epsilon-globin gene.
per: Proudfoot, N, et al.
Publicat: (1979)

Molecular rearrangements of the human alpha-globin gene cluster.
per: Higgs, D, et al.
Publicat: (1985)

COMPARISON OF THE ALPHA-GLOBIN GENE-CLUSTER STRUCTURE IN PERISSODACTYLA
per: Flint, J, et al.
Publicat: (1990)

Alpha Thalassemia in Istanbul: Distribution of Deletions in Alpha-globin Gene Cluster
per: Fatma Nihal Öztürk
Publicat: (2024-06-01)

The primary structure of the human epsilon-globin gene.
per: Baralle, F, et al.
Publicat: (1980)

Understanding regulation of zeta-globin transcription as the first step towards embryonic globin induction in patients with severe alpha-thalassemia
per: Songdej, D
Publicat: (2015)

The role of distal regulatory elements in alpha globin transcription
per: Hay, D
Publicat: (2014)

The evolution of the alpha- and beta-globin gene clusters in human populations.
per: Hill, A, et al.
Publicat: (1986)

The organization of the tadpole and adult alpha globin genes of Xenopus laevis.
per: Patient, R, et al.
Publicat: (1982)

Analysis of the human alpha-globin gene cluster in transgenic mice.
per: Sharpe, J, et al.
Publicat: (1993)

GLOBIN GENES AND MESSENGER-RNA FROM HUMANS WITH THALASSEMIA
per: Proudfoot, N, et al.
Publicat: (1979)

Platypus globin genes and flanking loci suggest a new insertional model for beta-globin evolution in birds and mammals
per: Warren Wesley C, et al.
Publicat: (2008-07-01)

The developmental regulation of the human zeta-globin gene in transgenic mice employing beta-galactosidase as a reporter gene.
per: Pondel, MD, et al.
Publicat: (1992)

Characterization of a novel HBB:c.194dup variant of the -globin gene combined with six alpha genes
per: Jungao Huang, et al.
Publicat: (2022-05-01)

The gene for theta-globin is transcribed in human fetal erythroid tissues.
per: Leung, S, et al.
Publicat: (1987)

The 5' flanking region of human epsilon-globin gene.
per: Baralle, F, et al.
Publicat: (1980)