Synergy between the C2 allele of transferrin and the C282Y allele of the haemochromatosis gene (HFE) as risk factors for developing Alzheimer's disease.

BACKGROUND: There is evidence that iron may play a role in the pathology of Alzheimer's disease (AD). There may be genetic factors that contribute to iron deposition resulting in tissue damage thus exacerbating AD. METHODS: We have genotyped 269 healthy elderly controls, 191 cases with definite...

Full description

Bibliographic Details
Main Authors: Robson, K, Lehmann, D, Wimhurst, V, Livesey, K, Combrinck, M, Merryweather-Clarke, A, Warden, DR, Smith, A
Format: Journal article
Language:English
Published: 2004