Molecular dissection of Alzheimer's disease neuropathology by depletion of serum amyloid P component.

New therapeutic approaches in Alzheimer's disease are urgently needed. The normal plasma protein, serum amyloid P component (SAP), is always present in cerebrospinal fluid (CSF) and in the pathognomonic lesions of Alzheimer's disease, cerebrovascular and intracerebral Abeta amyloid plaques...

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Bibliographic Details
Main Authors: Kolstoe, SE, Ridha, B, Bellotti, V, Wang, N, Robinson, C, Crutch, S, Keir, G, Kukkastenvehmas, R, Gallimore, JR, Hutchinson, W, Hawkins, P, Wood, S, Rossor, M, Pepys, M
Format: Journal article
Language:English
Published: 2009