Trans-ethnic Mendelian-randomization study reveals causal relationships between cardiometabolic factors and chronic kidney disease

<br><strong>Background<br></strong> This study was to systematically test whether previously reported risk factors for chronic kidney disease (CKD) are causally related to CKD in European and East Asian ancestries using Mendelian randomization. <br><strong> Method...

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Main Authors: Zheng, J, Zhang, Y, Rasheed, H, Walker, V, Sugawara, Y, Li, J, Leng, Y, Elsworth, B, Wootton, RE, Fang, S, Yang, Q, Burgess, S, Haycock, PC, Borges, MC, Cho, Y, Carnegie, R, Howell, A, Robinson, J, Thomas, LF, Brumpton, BM, Hveem, K, Hallan, S, Franceschini, N, Morris, AP, Köttgen, A, Pattaro, C, Wuttke, M, Yamamoto, M, Kashihara, N, Akiyama, M, Kanai, M, Matsuda, K, Kamatani, Y, Okada, Y, Walters, R, Millwood, IY, Chen, Z, Davey Smith, G, Barbour, S, Yu, C, Åsvold, BO, Zhang, H, Gaunt, TR
Format: Journal article
Language:English
Published: Oxford University Press 2021