Platelet-derived growth factor-beta receptor activation is essential for fibroblast and pericyte recruitment during cutaneous wound healing.

Connective tissue remodeling provides mammals with a rapid mechanism to repair wounds after injury. Inappropriate activation of this reparative process leads to scarring and fibrosis. Here, we studied the effects of platelet-derived growth factor receptor-beta blockade in vivo using the platelet-der...

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Bibliographic Details
Main Authors: Rajkumar, V, Shiwen, X, Bostrom, M, Leoni, P, Muddle, J, Ivarsson, M, Gerdin, B, Denton, C, Bou-Gharios, G, Black, C, Abraham, D
Format: Journal article
Language:English
Published: 2006