Platelet-derived growth factor-beta receptor activation is essential for fibroblast and pericyte recruitment during cutaneous wound healing.
Connective tissue remodeling provides mammals with a rapid mechanism to repair wounds after injury. Inappropriate activation of this reparative process leads to scarring and fibrosis. Here, we studied the effects of platelet-derived growth factor receptor-beta blockade in vivo using the platelet-der...
Հիմնական հեղինակներ: | Rajkumar, V, Shiwen, X, Bostrom, M, Leoni, P, Muddle, J, Ivarsson, M, Gerdin, B, Denton, C, Bou-Gharios, G, Black, C, Abraham, D |
---|---|
Ձևաչափ: | Journal article |
Լեզու: | English |
Հրապարակվել է: |
2006
|
Նմանատիպ նյութեր
-
Microvascular Pericytes undergo a phenotypic change during dermal wound healing.
: Rajkumar, V, և այլն
Հրապարակվել է: (2002) -
Gene expression profiling of fibroblasts in response to applied bio-mechanical force
: Eastwood, M, և այլն
Հրապարակվել է: (2007) -
Bosentan attenuates the profibrotic gene expression profile of lung fibroblasts in scleroderma
: Shiwen, X, և այլն
Հրապարակվել է: (2006) -
Response of human lung fibroblast cells to stimulation by endothelin-1: Involvement of ras/MEK/ERK and PI3 kinase
: Shiwen, X, և այլն
Հրապարակվել է: (2003) -
GENE EXPRESSION PROFILING OF CONNECTIVE TISSUE FIBROBLASTS IN RESPONSE TO APPLIED BIO-MECHANICAL FORCE
: Shiwen, X, և այլն
Հրապարակվել է: (2003)