Markov models for ion channels: versatility versus identifiability and speed.
Markov models (MMs) represent a generalization of Hodgkin-Huxley models. They provide a versatile structure for modelling single channel data, gating currents, state-dependent drug interaction data, exchanger and pump dynamics, etc. This paper uses examples from cardiac electrophysiology to discuss...
Main Authors: | Fink, M, Noble, D |
---|---|
Format: | Journal article |
Sprog: | English |
Udgivet: |
2009
|
Lignende værker
-
From Brownian Dynamics to Markov Chain: an Ion Channel Example
af: Chen, W, et al.
Udgivet: (2012) -
From Brownian dynamics to Markov chain: an ion channel example
af: Chen, W, et al.
Udgivet: (2012) -
CHAP: A versatile tool for the structural and functional annotation of ion channel pores
af: Klesse, G, et al.
Udgivet: (2019) -
Modelling effects of Sotalol on Action Potential morphology using a novel Markov model of the HERG channel
af: Brennan, T, et al.
Udgivet: (2007) -
Modelling effects of Sotalol on Action Potential morphology using a novel Markov model of the HERG channel
af: Brennan, T, et al.
Udgivet: (2007)