Functional identification of islet cell types by electrophysiological fingerprinting

The α-, β- and δ-cells of the pancreatic islet exhibit different electrophysiological features. We used a large dataset of whole-cell patch-clamp recordings from cells in intact mouse islets (N=288 recordings) to investigate whether it is possible to reliably identify cell type (α, β or δ) based on...

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Main Authors: Briant, L, Zhang, Q, Vergari, E, Kellard, J, Rodriguez, B, Ashcroft, F, Rorsman, O
格式: Journal article
出版: Royal Society 2017