Functional identification of islet cell types by electrophysiological fingerprinting
The α-, β- and δ-cells of the pancreatic islet exhibit different electrophysiological features. We used a large dataset of whole-cell patch-clamp recordings from cells in intact mouse islets (N=288 recordings) to investigate whether it is possible to reliably identify cell type (α, β or δ) based on...
Huvudupphovsmän: | Briant, L, Zhang, Q, Vergari, E, Kellard, J, Rodriguez, B, Ashcroft, F, Rorsman, O |
---|---|
Materialtyp: | Journal article |
Publicerad: |
Royal Society
2017
|
Liknande verk
Liknande verk
-
Electrophysiology of pancreatic β-cells in intact mouse islets of Langerhans.
av: Rorsman, P, et al.
Publicerad: (2011) -
Electrophysiology of the pancreatic beta-cell.
av: Ashcroft, F, et al.
Publicerad: (1989) -
Beta-cell hubs maintain Ca2+ oscillations in human and mouse islet simulations
av: Lei, C, et al.
Publicerad: (2018) -
Cellular function in multicellular system for hormone-secretion: electrophysiological aspect of studies on alpha-, beta- and delta-cells of the pancreatic islet.
av: Kanno, T, et al.
Publicerad: (2002) -
Electrophysiological and metabolic characterization of single beta-cells and islets from diabetic GK rats.
av: Hughes, S, et al.
Publicerad: (1998)