ERAD‐dependent control of the Wnt secretory factor Evi

Active regulation of protein abundance is an essential strategy to modulate cellular signaling pathways. Within the Wnt signaling cascade, regulated degradation of β‐catenin by the ubiquitin‐proteasome system (UPS) affects the outcome of canonical Wnt signaling. Here, we found that abundance of the...

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Bibliographic Details
Main Authors: Glaeser, K, Urban, M, Fenech, E, Voloshanenko, O, Kranz, D, Lari, F, Christianson, J, Boutros, M
Format: Journal article
Published: EMBO Press 2018