Mathematical modeling of monoclonal conversion in the colonic crypt
A novel spatial multiscale model of a colonic crypt is described, which couples the cell cycle (including cell division) with the mechanics of cell movement. The model is used to investigate the process of monoclonal conversion under two hypotheses concerning stem cell behavior. Under the first hypo...
| Main Authors: | , , |
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| Format: | Journal article |
| Published: |
Elsvier
2012
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