Diagnosing severe falciparum malaria in parasitaemic African children: a prospective evaluation of plasma PfHRP2 measurement.

BACKGROUND: In African children, distinguishing severe falciparum malaria from other severe febrile illnesses with coincidental Plasmodium falciparum parasitaemia is a major challenge. P. falciparum histidine-rich protein 2 (PfHRP2) is released by mature sequestered parasites and can be used to esti...

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Main Authors: Hendriksen, I, Mwanga-Amumpaire, J, von Seidlein, L, Mtove, G, White, L, Olaosebikan, R, Lee, S, Tshefu, A, Woodrow, C, Amos, B, Karema, C, Saiwaew, S, Maitland, K, Gomes, E, Pan-Ngum, W, Gesase, S, Silamut, K, Reyburn, H, Joseph, S, Chotivanich, K, Fanello, C, Day, N, White, N, Dondorp, A
Format: Journal article
Language:English
Published: Public Library of Science 2012