DNA methylation age mediates effect of metabolic profile on cardiovascular and general aging

<p><strong>BACKGROUND: </strong>Alterations in lipid metabolism and DNA methylation are 2 hallmarks of aging. Connecting metabolomic, epigenomic, and aging outcomes help unravel the complex mechanisms underlying aging. We aimed to assess whether DNA methylation clocks mediate the a...

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Bibliografski detalji
Glavni autori: Si, J, Ma, Y, Yu, C, Sun, D, Pang, Y, Pei, P, Yang, L, Millwood, IY, Walters, RG, Chen, Y, Du, H, Zheng, X, Avery, D, Chen, J, Chen, Z, Liang, L, Li, L, Lv, J
Daljnji autori: China Kadoorie Biobank Collaborative Group
Format: Journal article
Jezik:English
Izdano: American Heart Association 2024