Fetal liver hepcidin secures iron stores in utero

Fetal liver hepcidin secures iron stores in utero

In the adult, the liver-derived hormone hepcidin (HAMP) controls systemic iron levels by blocking the iron-exporting protein ferroportin (FPN) in the gut and spleen, the sites of iron absorption and recycling respectively. Impaired HAMP expression or FPN responsiveness to HAMP result in iron overloa...

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Bibliografiske detaljer
Main Authors:	Kämmerer, L, Mohammad, G, Wolna, M, Robbins, P, Lakhal-Littleton, S
Format:	Journal article
Sprog:	English
Udgivet:	American Society of Hematology 2020

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