Fetal liver hepcidin secures iron stores in utero

Fetal liver hepcidin secures iron stores in utero

In the adult, the liver-derived hormone hepcidin (HAMP) controls systemic iron levels by blocking the iron-exporting protein ferroportin (FPN) in the gut and spleen, the sites of iron absorption and recycling respectively. Impaired HAMP expression or FPN responsiveness to HAMP result in iron overloa...

Полное описание

Библиографические подробности
Главные авторы:	Kämmerer, L, Mohammad, G, Wolna, M, Robbins, P, Lakhal-Littleton, S
Формат:	Journal article
Язык:	English
Опубликовано:	American Society of Hematology 2020

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